Mary Ashe Miller was the only child of Ann Eliza to marry.
Mary Miller married Charles Boyd Tyler, a cotton merchant in Atlanta, GA on 8 April 1885. They had two children: Sarah Ashe Tyler and Charles Boyd, Jr. Sarah married Robert R. Dillingham who lived only a short while and left no issue. Charles Boyd, Jr. also married but left no issue. Thus Ann Eliza has no direct descendants.